Silhueta de pessoa indiferenciada

Isabel Maria Palma Antunes Cavaco

Professor associado
Subsistema
Docentes Universitário
Regime
Exclusividade
Vínculo
CT em Funções Públicas por tempo indeterminado

Projetos

Projetos
2020/10/01 - 2026/10/01. ChIR: Erasmus Mundus MSc in Chemical Innovation and Regulation, Erasmus+ / Erasmus Mundus. Investigador responsável. Universidade do Algarve - Faculdade de Ciências e Tecnologia - Departamento de Química e Farmácia .
2012/10/01 - 2019/10/01. EMMC-ChIR: Erasmus Mundus Master in Chemical Innovation and Regulation, Erasmus+ / KA2 / Erasmus Mundus Joint Master Degrees. Investigador responsável. Universidade do Algarve - Campus de Gambelas.
2013/06/01 - 2016/12/31. Do desenvolvimento de novos produtos bioactivos à descoberta de novos materiais funcionais: uma abordagem estrutural em áreas emergentes, 3599-PPCDT. Universidade de Lisboa Centro de Química Estrutural; Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento.
2013/06 - 2016/05. From drug design to new materials: structural approach in emergent fields. Investigador.
2008/09 - 2015/03. EMQAL - European Master in Quality in Analytical Laboratories, Erasmus Mundus. Investigador responsável.
2010/01/01 - 2013/06/30. Complexos de Ruténio para aplicação anti-tumoral, 3599-PPCDT. Fundação da Faculdade de Ciências da Universidade de Lisboa; Universidade de Lisboa Faculdade de Ciências; Universidade de Lisboa Instituto Superior Técnico.
2010/01 - 2013/06. Ruthenium complexes for anti-tumour application. Investigador.
2007/01 - 2009/08. Design of new Vanadium compounds: towards their application as anti-diabetic and anti-cancer agents. Investigador.
2005/10/01 - 2007/06/30. Desenvolvimento de novos compostos de Vanádio. Sua aplicação como agentes antidiabéticos e anticancerígenos, POCI. Universidade de Lisboa Instituto Superior Técnico; Universidade de Lisboa Centro de Química Estrutural; Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares; Universidade de Coimbra Centro de Neurociências e Biologia Celular.
2005/10 - 2007/06. Design of new Vanadium compounds: towards their application as anti-diabetic and anti-cancer agents. Investigador.
2002/01 - 2005/01. Vanadium carriers for Permeation Liquid Membranes (PLM): optimization for speciation of vanadium(IV), POCTI. Investigador responsável.
2002/01/01 - 2004/12/31. Transportadores de vanádio em membranas líquidas permeáveis: optimização para especiação de vanádio(IV), POCI.
2002/01/01 - 2004/12/31. Transportadores de vanádio em membranas líquidas permeáveis: optimização para especiação de vanádio(IV), POCI.
2001 - 2004. Cadmium and vanadium compounds interactions with sarcoplasmic reticulum calcium pump. Investigador.
2001 - 2004. Trace metal speciation in natural waters using Permeation Liquid Membranes (PLM). Investigador.

Produções

Butenko, Nataliya; Tomaz, Ana Isabel; Nouri, Ofelia; Escribano, Esther; Moreno, Virtudes; Gama, Sofia; Ribeiro, Vera; et al. 2009. "DNA cleavage activity of VIVO(acac)2 and derivatives". Journal of Inorganic Biochemistry, 103 (4): 622-632. https://doi.org/10.1016/j.jinorgbio.2009.01.003
Di Virgilio, Ana L.; Rivadeneira, Josefina; Muglia, Cecilia I.; Reigosa, Miguel A.; Butenko, Nataliya; Cavaco, Isabel; Etcheverry, Susana B.. 2011. "Cyto- and genotoxicity of a vanadyl(IV) complex with oxodiacetate in human colon adenocarcinoma (Caco-2) cells: potential use in cancer therapy". BioMetals, 24 (6): 1153-1168. https://doi.org/10.1007/s10534-011-9474-x
Naso, Luciana G.; Ferrer, Evelina G.; Butenko, Nataliya; Cavaco, Isabel; Lezama, Luis; Rojo, Teófilo; Etcheverry, Susana B.; Williams, Patricia A. M.. 2011. "Antioxidant, DNA cleavage, and cellular effects of silibinin and a new oxovanadium(IV)/silibinin complex". JBIC Journal of Biological Inorganic Chemistry, 16 (4): 653-668. https://doi.org/10.1007/s00775-011-0769-8
Yang, Yang; Ferro, Miguel Duarte; Cavaco, Isabel; Liang, Yizeng. 2013. "Detection and Identification of Extra Virgin Olive Oil Adulteration by GC-MS Combined with Chemometrics". Journal of Agricultural and Food Chemistry, 61 (15): 3693-3702. https://doi.org/10.1021/jf4000538
Cavaco, Isabel Maria Palma Antunes; León, I.E.; Butenko, N.; Baran, E.; Etcheverry, S.B.. 2011. "PLASMID DNA CLEAVAGE AND CYTOTOXICITY OF VO(oda)phen COMPLEX ON NORMAL AND TUMOR LINES INCULTURE". Trabalho apresentado em 47th annual meeting of the Argentine Society for Biochemistry and Molecular Biology, Potrero de los Funes, San Luis, 2011 (35), 70-70.
Cavaco, Isabel Maria Palma Antunes; Butenko, N.; Tomaz, Isabel; Ribeiro, Vera; Pesssoa, João Costa. 2009. "Studies on the mechanism of action of an efficient vanadium inorganic nuclease, VIVO(acac)2". Trabalho apresentado em 14th International Conference on Biological Inorganic Chemistry, Nagoya, 2009 (14), S183-S183.
Cavaco, Isabel Maria Palma Antunes. 2017. "Interaction of [VIVO(acac)2] with Human Serum Transferrin and Albumin". Chemistry an Asian Journal. https://doi.org/10.1002/asia.201700469
Ribeiro, Nádia; Roy, Somnath; Butenko, Nataliya; Cavaco, Isabel; Pinheiro, Teresa; Alho, Irina; Marques, Fernanda; et al. 2017. "New Cu(II) complexes with pyrazolyl derived Schiff base ligands: Synthesis and biological evaluation". Journal of Inorganic Biochemistry, 174: 63-75. https://doi.org/10.1016/j.jinorgbio.2017.05.011
Correia, I.; Roy, S.; Matos, C.P.; Borovic, S.; Butenko, N.; Cavaco, I.; Marques, F.; et al. 2015. "Vanadium(IV) and copper(II) complexes of salicylaldimines and aromatic heterocycles: Cytotoxicity, DNA binding and DNA cleavage properties". Journal of Inorganic Biochemistry, 147: 134-146. https://doi.org/10.1016/j.jinorgbio.2015.02.021
Butenko, N.; Pinheiro, J.P.; Da Silva, J.P.; Tomaz, A.I.; Correia, I.; Ribeiro, V.; Costa Pessoa, J.; Cavaco, I.. 2015. "The effect of phosphate on the nuclease activity of vanadium compounds". Journal of Inorganic Biochemistry, 147: 165-176. https://doi.org/10.1016/j.jinorgbio.2015.04.010
Cavaco, Isabel Maria Palma Antunes. 2013. "Vanadium and cancer treatment: Antitumoral mechanisms of three oxidovanadium(IV) complexes on a human osteosarcoma cell line". https://doi.org/10.1016/j.jinorgbio.2013.10.009
Cobbina, E.; Mehtab, S.; Correia, I.; Gonçalves, G.; Tomaz, I.; Cavaco, I.; Jakusch, T.; et al. 2013. "Binding of Oxovanadium(IV) complexes to blood serum albumins". Journal of the Mexican Chemical Society, 57 (3): 180-191. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885214174&partnerID=MN8TOARS
Pessoa, J.C.; Cavaco, I.; Correia, I.; Tomaz, I.; Adão, P.; Vale, I.; Ribeiro, V.; Castro, M.M.C.A.; Geraldes, C.C.F.G.. 2007. Vanadium schiff base complexes: Chemistry, properties, and concerns about possible therapeutic applications. Vol. 974. http://www.scopus.com/inward/record.url?eid=2-s2.0-36749027238&partnerID=MN8TOARS
Cavaco, Isabel Maria Palma Antunes. 2004. "N-Salicylideneamino acidato complexes of oxovanadium(iv). The cysteine and penicillamine complexes". https://doi.org/10.1039/b404305g
Costa Pessoa, J.; Calhorda, M.J.; Cavaco, I.; Correia, I.; Duarte, M.T.; Felix, V.; Henriques, R.T.; Piedadea, M.F.M.; Tomaza, I.. 2002. "Molecular modelling studies of N-salicylideneamino acidato complexes of oxovanadium(IV). Molecular and crystal structure of a new dinuclear LOVIV-O-VvOL mixed valence complex". Journal of the Chemical Society, Dalton Transactions, (23): 4407-4415. https://doi.org/10.1039/b205843j
Costa Pessoa, J.; Cavaco, I.; Correia, I.; Tomaz, I.; Duarte, T.; Matias, P.M.. 2000. "Oxovanadium(IV) complexes with aromatic aldehydes". Journal of Inorganic Biochemistry, 80 (1-2): 35-39. https://doi.org/10.1016/S0162-0134(00)00037-4
Pessoa, J.C.; Cavaco, I.; Correia, I.; Duarte, M.T.; Gillard, R.D.; Henriques, R.T.; Higes, F.J.; et al. 1999. "Preparation and characterisation of new oxovanadium(IV) Schiff base complexes derived from amino acids and aromatic o-hydroxyaldehydes". Inorganica Chimica Acta, 293 (1): 1-11. https://doi.org/10.1016/S0020-1693(00)00102-X
Bernalte, A.; Barros, F.J.G.; Cavaco, I.; Pessoa, J.C.; Gillard, R.D.; Higes, F.J.; Tomaz, I.. 1998. "X-ray characterization of an unusual product obtained from [VO(Sal-Phe)(H2O)] in H2O\pyridine solutions". Polyhedron, 17 (19): 3269-3274. https://doi.org/10.1016/S0277-5387(98)00105-3
Cavaco, I.; Pessoa, J.C.; Duarte, M.T.; Gillard, R.D.; Matias, P.. 1996. "Molecular structure of [VO(sal-D,L-Asn)(py)(H2O)] and reaction to produce coumarin-3-carboxamide". Chemical Communications, (11): 1365-1366. https://doi.org/10.1039/cc9960001365
Cavaco, I.; Costa Pessoa, J.; Duarte, M.T.; Henriques, R.T.; Matias, P.M.; Gillard, R.D.. 1996. "Crystal and molecular structure of [V2O3(sal-L-val)2(H2O)] (sal-L-val = N-salicylidene-L-valinate) and spectroscopic properties of related complexes". Journal of the Chemical Society - Dalton Transactions, (9): 1989-1996. https://doi.org/10.1039/dt9960001989
Cavaco, I.; Pessoa, J.C.; Luz, S.M.; Duarte, M.T.; Matias, P.M.; Henriques, R.T.; Gillard, R.D.. 1995. "N-salicylideneamino-acidate complexes of oxovanadium(IV)-II. Synthesis, characterization and deamination of an n-salicylideneglycylglycinato complex". Polyhedron, 14 (3): 429-439. https://doi.org/10.1016/0277-5387(94)00247-C
Costa Pessoa, J.; Luz, S.M.; Cavaco, I.; Gillard, R.D.. 1994. "Oxovanadium(IV) and amino acids-VII. The system l-histidine+VO2+; a self-consistent potentiometric and spectroscopic study". Polyhedron, 13 (23): 3177-3198. https://doi.org/10.1016/S0277-5387(00)83381-1
Cavaco, Isabel; Pessoa, Jo�o Costa; Costa, Dina; Duarte, Maria T.; Gillard, Robert D.; Matias, Pedro; Cavaco, I.; et al. 1994. "N-salicylideneamino acidate complexes of oxovanadium(IV). Part 1. Crystal and molecular structures and spectroscopic properties". Journal of the Chemical Society, Dalton Transactions, (2): 149-149. https://doi.org/10.1039/dt9940000149
Cavaco, I.; Pessoa, J.C.; Duarte, M.T.; Matias, P.M.; Henriques, R.T.; Cavaco, Isabel Maria Palma Antunes. 1993. "Synthesis and structural characterization of a polyoxovanadate coordination complex [V4O8(CH3O)4(bipy)2] with a tetrametallate core". Polyhedron, 12 (10): 1231-1237. https://doi.org/10.1016/S0277-5387(00)88216-9
Tsenkova, Boryana Krasimirova. 2017. "Synthesis and characterization of ionic co-crystals of enantiopure and racemic proline". Mestrado. http://hdl.handle.net/10400.1/10161
Talampas, Shella Ira. 2017. "Study on the different strategies and approaches followed by companies in Portugal and Spain to comply with reach regulations". Mestrado. http://hdl.handle.net/10400.1/10237
Alemu, Yemataw Addis. 2017. "Synthesis, characterization and biological evaluation of zinc(ii) complexes with phenanthroline derivatives and s-methyl dithiocarbazate schiff bases". Mestrado. http://hdl.handle.net/10400.1/10160
Duarte, Cátia Patrícia Cardoso. 2017. "Avaliação do teor de metais de transição em efluentes urbanos tratados na região do Algarve, tendo em vista o seu impacte ambiental". Mestrado. http://hdl.handle.net/10400.1/10164
Gonzaga, Loveille Jun Amarille. 2017. "Isolation and identification of secondary metabolites from the bryozoan Cryptosula zavjalovensis from Hokkaido, Japan". Mestrado. http://hdl.handle.net/10400.1/10157
Narmandakh, Bazarsad. 2016. "Coal fuel gas cleaning by non-thermal pulsed corona discharge plasma and “reach” regulation compatibility assessemnt for trace elements extraction from gasification ash". Mestrado. http://hdl.handle.net/10400.1/9823
Karengera, Antoine. 2015. "Evaluation of the cytotoxicity of transition metal complexes: DNA cleavage of copper complexes in cells". Mestrado. http://hdl.handle.net/10400.1/7862
Wang, Wei. 2016. "Risk to patient safety from laboratory errors and delays". Mestrado. http://hdl.handle.net/10400.1/9842
Karmacharya, Amresh Prasad. 2015. "Validation of a method for the analysis of volatile organic compounds in water". Mestrado. http://hdl.handle.net/10400.1/7843
Medina Martínez, Ana Maria. 2014. "Transport in the blood of an anti-tumor water-soluble rutheniun cyclopentadienyl complex: a fluorescence study on albumin binding". Mestrado. http://hdl.handle.net/10400.1/8664
Visekruna, Jovana. 2015. "DRIFT and DRUV spectroscopy methods for studying the interaction of metal compounds with native cellulose". Mestrado. http://hdl.handle.net/10400.1/7948
Chorna, Ielyzaveta. 2015. "Evaluation of the binding of vanadium-based anticancer drugs to human serum proteins". Mestrado. http://hdl.handle.net/10400.1/7947
Elwany, Saber Saoud Abdalla. 2014. "Design of a new laboratory for quality control of mussel produced in Sagres". Mestrado. http://hdl.handle.net/10400.1/8663
Butenko, Nataliya. 2013. "Interaction of vanadium compounds with DNA". Doutoramento. http://hdl.handle.net/10400.1/6864
Subedi, Prabal. 2012. "Development of a new method for the detection of vanadium complexes bound to DNA, using Agarose Gel Electrophoresis". Mestrado. http://hdl.handle.net/10400.1/2743
Zajac, Alena. 2011. "Implementation of a quality system in joint master programmes". Mestrado. http://hdl.handle.net/10400.1/5739
Ferro, Miguel Duarte. 2013. "Chromatographic analysis and comparison of chemical composition of the samples between olive oils in Europe and some chinese oils". Mestrado. http://hdl.handle.net/10400.1/3643
Herendi, Lili. 2012. "Optimization and validation of a method for the analysis of volatile organic compounds in water intended for human consumption by SPME-GC-MS". Mestrado. http://hdl.handle.net/10400.1/10492
Mbenju, John Ekaney. 2012. "Optimization and validation of a method for the analysis of target compounds migrating from organic materials used in contact with water intended for human consumption by SPME-GC-TOFMS". Mestrado. http://hdl.handle.net/10400.1/2887
Cakaj, Fatmir. 2011. "DR-UV/vis spectroscopy for studying the interaction of vanadium compounds with cellulose". Mestrado. http://hdl.handle.net/10400.1/4526
Haule, Elizabeth. 2011. "Obstacles towards laboratory accreditation in Africa- the case of Tanzania". Mestrado. http://hdl.handle.net/10400.1/10963
Cobbina, Enoch. 2011. "Spectroscopic study of VIVO2+ binding on serum albumins". Mestrado. http://hdl.handle.net/10400.1/10967
Takyi-Williams, John. 2011. "Analysis of target organic compounds which migrate from organic materials used in contact with drinking water: development and validation of analytical method using LLE-GC-ITMS". Mestrado. http://hdl.handle.net/10400.1/11068
Borovic, Sladana. 2012. "Copper complexes as therapeutic drugs: use of analytical / spectroscopic methods for the evaluation of their transport in blood". Mestrado. http://hdl.handle.net/10400.1/10635
Melo, Maria João Salgado e. 2008. "Implementação de um sistema da qualidade no serviço de imuno-hemoterapia do Hospital Central de Faro". Mestrado. http://hdl.handle.net/10400.1/651
Soeiro, Teresa Margarida Viegas Cabrita. 2006. "Implementação de um sistema da qualidade num laboratório de aulas de engenharia alimentar". Mestrado. http://hdl.handle.net/10400.1/725
Cavaco, Isabel; correia, isabel; Borovic, Sladana; Matos, Cristina; Roy, Somnath; Santos, Hugo; Fernandes, Luz; et al. Autor correspondente: Costa Pessoa, João. 2017. "Evaluation of the binding of four anti-tumor Casiopeínas® to human serum albumin". Journal of Inorganic Biochemistry, 175: 284-297. https://doi.org/10.1016/j.jinorgbio.2017.07.025
Ruiz, Maria Carolina; Resasco, Agustina; Di Virgilio, Ana Laura; Ayala, Miguel; Cavaco, Isabel; Cabrera, Silvia; Aleman, Jose; León, Ignacio Esteban. 2019. "In vitro and in vivo anticancer effects of two quinoline–platinum(II) complexes on human osteosarcoma models". Cancer Chemotherapy and Pharmacology, 83 (4): 681-692. https://doi.org/10.1007/s00280-019-03773-x
Matos, Cristina P.; Addis, Yemataw; Nunes, Patrique; Barroso, Sónia; Alho, Irina; Martins, Marta; Matos, António P.A.; et al. 2019. "Exploring the cytotoxic activity of new phenanthroline salicylaldimine Zn(II) complexes". Journal of Inorganic Biochemistry, 198. https://doi.org/10.1016/j.jinorgbio.2019.110727
Cavaco, Isabel. 1998. "Síntese e Caracterização de Complexos de Vanádio com Ligandos de Interesse Biológico". Doutoramento.
Nádia Ribeiro; Adelino M. Galvão; Clara S. B. Gomes; Helena Ramos; Rute Pinheiro; Lucília Saraiva; Epole Ntungwe; et al. 2019. "Naphthoylhydrazones: coordination to metal ions and biological screening". New Journal of Chemistry. https://doi.org/10.1039/C9NJ01816F
Loveille Jun Gonzaga; Isabel Cavaco; Helena Fortunato. 2021. "Cytotoxicity of Cryptosula zavjalovensis Kubanin extract against Breast Cancer Cell Line MCF7". Acta Poloniae Pharmaceutica - Drug Research. https://doi.org/10.32383/appdr/139634
Ramilo-Gomes, F.; Addis, Y.; Tekamo, I.; Cavaco, I.; Campos, D.L.; Pavan, F.R.; Gomes, C.S.B.; et al. 2021. "Antimicrobial and antitumor activity of S-methyl dithiocarbazate Schiff base zinc(II) complexes". Journal of Inorganic Biochemistry, 216. https://doi.org/10.1016/j.jinorgbio.2020.111331
Nunes, P.; Correia, I.; Cavaco, I.; Marques, F.; Pinheiro, T.; Avecilla, F.; Pessoa, J.C.. 2021. "Therapeutic potential of vanadium complexes with 1,10-phenanthroline ligands, quo vadis? Fate of complexes in cell media and cancer cells". Journal of Inorganic Biochemistry, 217. https://doi.org/10.1016/j.jinorgbio.2020.111350
Talampas, S.I.; Cavaco, I.; Sainz, D.. 2020. "Strategies and approaches of companies in portugal and spain in complying with the REACH regulation". Mindanao Journal of Science and Technology, 18 (2): 26-55. http://www.scopus.com/inward/record.url?eid=2-s2.0-85097452087&partnerID=MN8TOARS
Nunes, P.; Correia, I.; Marques, F.; Matos, A.P.; Dos Santos, M.M.C.; Azevedo, C.G.; Capelo, J.-L.; et al. 2020. "Copper Complexes with 1,10-Phenanthroline Derivatives: Underlying Factors Affecting Their Cytotoxicity". Inorganic Chemistry, 59 (13): 9116-9134. https://doi.org/10.1021/acs.inorgchem.0c00925
Nunes, P.; Marques, F.; Cavaco, I.; Costa Pessoa, J.; Correia, I.. 2020. "Exploring the therapeutic potential of Cu(II)-complexes with ligands derived from pyridoxal". Inorganica Chimica Acta, 507. https://doi.org/10.1016/j.ica.2020.119558
 

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