José Bragança

 

University of Algarve

Department of Biomedical Sciences and Medicine, Bld 8

Phone: +351 289 244 483 (internal extn. 7483)

Email: jebraganca@ualg.pt

 

Academic Degrees

  • 1998 PhD, Molecular and Cellular Biology at the University of Paris XI, France.

 

Positions

  • 2009 – Present,  Assistant Professor, Department of Biomedical Sciences and Medicine, University of Algarve
  • 2008 – 2009,  ”Investigador Auxiliar” in the Animal Cell Technology laboratory at the ITQB/IBET – Portugal
  • 1999 – 2007, Post-doctoral Research Fellow in the research group directed by Professor Shoumo Bhattacharya in the Department of Cardiovascular Medicine directed by Professor Hugh Watkins at the University of Oxford, UK.

 

Research Interests

Our group is interested in genes and regulatory pathways that control mouse embryonic stem cells self-renewal and differentiation. The long-term aim of our work is to understand the molecular mechanisms involved in stem cell pluripotency and differentiation processes occurring in mouse and human cells in order to achieve cell-types specification in vitro for therapeutic purposes.

 

Project Grants

PTDC/SAU-ENB/111702/2009 (2011-2013) - miPS and hiPS: reprogramming mouse and human adult cells. Coordinator.

PTDC/SAU-SAP/111908/2009BIOMINEN (BIOMarkers in materno-Infant health related to ENvironmental factors). Collaborator.

Foundation Merck Sharp and Dhome – Portugal (October 2010 – June 2011) - miPS: reprogramming mouse adult cells. Coordinator.

2009 - Bolsas Cientificas de Instalação - Professor Doutor António Xavier 2009, Câmara Municipal de Oeiras.

 

Selected Publications (2008-2012)

MacDonald ST, Bamforth  SD, Bragança  J, Chen C-M,  Broadbent  C, Schneider JE, Schwartz  RJ and Bhattacharya S – “A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development” – Eur Heart J - 2012 Apr 14. [Epub ahead of print] DOI: 10.1093/eurheartj/ehs056.

Bernardino L,  Eiriz MF, Santos T, Xapelli S, Grade S, Rosa AI, Cortes L, Ferreira R, Bragança J, Agasse F, Ferreira L and Malva JO – “Histamine Stimulates Neurogenesis in the Rodent Subventricular Zone” – Stem cell, 30, 773-784 (2012). DOI: 10.1002/stem.104

Bragança J, Tavares A and Belo JA – “Células estaminais e medicina regenerativa – um admirável mundo novo” - Canal BQ, 7, 4-17 (2010).

Correia R and Bragança J - "Células estaminais adultas em medicina" - Canal BQ, 7, 18-23 (2010).

Michell, A. C. , Bragança J., Broadbent, C., Joyce, B., Franklyn, A., Schneider, J. E., Bhattacharya, S., Bamforth, S. D. "A novel role for transcription factor Lmo4 in thymus development through genetic interaction with Cited2", Developmental dynamics, 2010, doi 10.1002/dvdy.22334.

Stevens J, Ermakov A, Bragança J, Hilton H, Underhill P, Bhattacharya S, Brown N and Norris DP – “Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a Nodal-independent left sided signal and an early, left-right independent role for nodal flow” – BMC Developmental Biology 2010, 10:54 doi:10.1186/1471-213X-10-54.

 

 

 

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