Silhueta de pessoa indiferenciada

Joana Gonçalves de Gouveia Maia Xavier

Investigador doutorado
Subsistema
Investigadores
Regime
Exclusividade
Vínculo
CT em Funções Públicas a termo resolutivo certo

Atividades

Atividades
2021/10/14 - 2021/10/15. Participação em evento. Attendance to the International Meeting - Current Trends in Precision Medicine in Cancer. Encontro. II ASPIC-ASEICA International Meeting – Current Trends in Precision Medicine in Cancer.
2021/10/08 - 2021/10/08. Participação em evento. Invited lecture entitled An Introduction to Breast Cancer. Simpósio. Outubro Rosa Liga Portuguesa (Breast Cancer awareness initiative). Liga Portuguesa Contra o Cancro.
2021/08/31 - 2021/08/31. Entrevista / Programa (rádio / tv). RTP dias do Futuro (Antena 1). Investigation currently developed and the BfK Ideas price achieved.
2021/08/06. Apresentação oral de trabalho. Allelic expression imbalance of PIK3CA mutations in breast cancer is frequent and prognostically significant. Worldwide PI3K Zoom seminar series. Host Lab: CellSig (Prof B. Vanhaesebroeck), UCL, Cancer Institute, London.
2021/07/08 - 2021/07/15. Participação em evento. Development of a business idea: expressPIK - the RNA test specific to identify patients with breast cancer eligible for an innovative treatment.
Team: Ana Teresa Maia and Joana Xavier. . Concurso. BfK (Born from Knowledge) Ideas Contest 2020. Agência Nacional de Inovação SA.
2021/07/12. Apresentação oral de trabalho. A capacitação para o voluntariado: a experiência do Grupo de Voluntariado UAlg” V+. 7º Congresso Nacional de Práticas Pedagógicas no Ensino Superior (CNaPPES.21). Universidade de Aveiro (Aveiro, Portugal).
2021/05/20 - 2021/05/21. Participação em evento. Attendance to the Meeting - Stemness & Metastasis: Advances in Research and Clinical Translation. Encontro. Porto Cancer Meeting - Stemness & Metastasis: Advances in Research and Clinical Translation. Universidade do Porto.
2021/05/18 - 2021/05/19. Participação em evento. Attendance to the Virtual Conference on Bioinformatics in Cancer. Conferência. The European Association for Cancer Research (EACR) Virtual Conference on Bioinformatics in Cancer. European Association For Cancer Research.
2021/05/01 - Presente. Membro de comissão. Member of the coordination committee of the UAlg V+ Group (Volunteering Group from the University of Algarve) as Faculty of Medicine and Biomedical Sciences (FMCB) representative since May 2021.. Membro. Universidade do Algarve.
2021/02/08 - 2021/02/10. Participação em evento. Attendance to the Genomic Regulation 2021: Focus on Cancer. Encontro. Genomic Regulation 2021: Focus on Cancer, Swiss Institute on Bioinformatics (SIB).
2021/01/26 - 2021/01/28. Participação em evento. Ensembl Browser Workshop. Oficina (workshop). Ensembl Browser Workshop. European Bioinformatics Institute.
2019/06/01 - 2020. Comissão de avaliação. Juri panel member (President) of an international tender for the recruitment of a post-doctoral associate researcher under the research project INTERGEN - INnovating breast cancer GWAS through inTEgRation of functional GENomics. Universidade do Algarve. Fundação para a Ciência e Tecnologia (FCT).
2019/09/01 - 2020. Comissão de avaliação. Juri panel member (vogal efectivo) of a research fellowship for the recruitment of a doctorate under the research project POCI-01-0145-FEDER-022184 GenomePT. Universidade do Algarve. Fundação para a Ciência e Tecnologia (FCT).
2020/10/06 - Presente. Curso / Disciplina lecionado. Oncogenética e Oncogenómica. Oncobiologia - Mecanismos Moleculares do Cancro (Mestrado). Universidade do Algarve Departamento de Ciências Biomédicas e Medicina.
2020/09/20 - 2020/09/20. Participação em evento. Attendance to Cancer Biology: From Basic To Translational Research. Simpósio. Liga Portuguesa Contra o Cancro.
2020/09/06 - Presente. Orientação. Study of the association of Allelic Expression (AE) ratios with BC clinical features .Oncobiologia - Mecanismos Moleculares do Cancro (Mestrado). Orientador de António Góis.
2020/07/01 - Presente. Orientação. Innovating breast cancer GWAS through inTEgRation of functional GENomics. Orientador de Marinella Ghezzo .
2020/06/22 - 2020/06/24. Participação em evento. Attendance to the American Association for Cancer Research (AACR) 2020 Virtual Annual Meeting II. Encontro. 2020 Virtual Annual Meeting II. American Association for Cancer Research.
2020/02/20 - 2020/02/20. Organização de evento. Organization of an activity entitled “Extraction of DNA from fruit” for middle school and high school students at the Open Day (Dia Aberto) from the University of Algarve (2020). Universidade do Algarve.
2019/12/09 - Presente. Arbitragem científica em revista. BMC Bioinformatics (1471-2105). Springer (Biomed Central Ltd.).
2019/09/29 - 2019/10/02. Participação em evento. Attendance to the EMBO | EMBL Symposium: Systems Genetics: From Genomes to Complex Traits. Simpósio. EMBO | EMBL Symposium: Systems Genetics: From Genomes to Complex Traits.
2019/07/30. Apresentação oral de trabalho. Innovating breast cancer GWAS through integration of functional Genomics.. CBMR scientific meeting. CBMR (Loulé, Portugal).
2017/09/03 - 2018/08/15. Orientação. Identifying novel genes associated with breast cancer susceptibility using differential allelic expression ratios.Oncobiologia - Mecanismos Moleculares do Cancro (Mestrado). Coorientador de Catarina Martins .
2018/01/26. Apresentação oral de trabalho. Uncovering miRNA-mediated cis-regulation in common cancers. . CIMAGO Scientific Meeting. CIMAGO (Coimbra, Portugal).
2017/11/17. Apresentação oral de trabalho. Mapping of cis-regulatory variants helps dissecting the risk mechanism for breast cancer associated 5q14.1 locus. 21ª Reunião da Sociedade Portuguesa de Genética Humana (SPGH). Sociedade Portuguesa de Genética Humana (SPGH) (Costa da Caparica, Portugal).
2017/11/17. Apresentação oral de trabalho. miRNA-mediated cis-regulation in breast cancer susceptibility. 21ª Reunião da Sociedade Portuguesa de Genetica Humana (SPGH). Sociedade Portuguesa de Genetica Humana (SPGH) (Costa da Caparica, Portugal).
2017/11/01 - Presente. Curso / Disciplina lecionado. Genética Humana. Ciências Biomédicas (Licenciatura). Universidade do Algarve Departamento de Ciências Biomédicas e Medicina.
2016/09/03 - 2017/08/15. Orientação. The role of miRNA-mediated cis-regulation in breast cancer susceptibility.Oncobiologia - Mecanismos Moleculares do Cancro (Mestrado). Coorientador de Ana Catarina Jacinta Fernandes.
2017/01/06 - 2017/02/10. Arbitragem científica em revista. Computer Methods and Programs in Biomedicine.
2015/02/01 - 2016/07/31. Orientação. Functional Characterisation of Putative Cis-Regulatory Risk Loci for Breast Cancer.EMQAL Erasmus Mundus (Mestrado). Coorientador de Noordiana Rosli.
2016/05/01 - 2016/06/30. Orientação. Estudo da influência de polimorfismos de risco para cancro da mama na regulação por miRNAs.Ciências Biomédicas (Licenciatura/Bacharelato). Coorientador de Pedro Conceição .
2015/11/29 - 2015/12/02. Participação em evento. Course on Analysis of High-throughput sequencing data with Bioconductor. Oficina (workshop). Analysis of High-throughput sequencing data with Bioconductor. University of Cambridge Centre for Applied Medical Statistics.
2015/05/01 - 2015/06/30. Orientação. Identificação de novos marcadores genéticos de risco para o cancro da mama.Bioquímica (Licenciatura/Bacharelato). Coorientador de Rita Simão.
2015/05/01 - 2015/06/30. Orientação. Identificação de novos marcadores genéticos de risco para cancro da mama.Ciências Biomédicas (Licenciatura/Bacharelato). Coorientador de Bernardo P Almeida.
2014/11/20. Apresentação oral de trabalho. Identification of 4 novel susceptibility loci for intracranial aneurysms in Portuguese using a pooling-based GWAS.. 18ª Reunião da Sociedade Portuguesa de Genetica Humana (SPGH). Sociedade Portuguesa de Genetica Humana (SPGH) (Lisboa, Portugal).
2014/05/01 - 2014/06/30. Orientação. Influência da variação genética na expressão de mutações em cancro.Ciências Biomédicas (Licenciatura/Bacharelato). Coorientador de Inês Gomes.
2013/11/22. Apresentação oral de trabalho. FUT2: filling the gap between genes and environment in Behçet’s disease? . 17th Annual Meeting of the Portuguese Society of Human Genetics. Sociedade Portuguesa de Genética Humana (SPGH) (Coimbra, Portugal).
2013/06/12. Apresentação oral de trabalho. Genome-wide association study identifies FUT2 as a novel genetic risk factor for Behçet’s disease. XXXVIII Jornadas Portuguesas de Genética.. Sociedade Portuguesa de Genetica (Porto, Portugal).
2013/04/04. Apresentação oral de trabalho. Identification of FUT2 as a risk factor for Behçet's disease in a genome-wide association study. Joint Conference of HGM and 21st International Congress of Genetics.
2012/11/11 - 2012/11/14. Participação em evento. Course on Automated and Reproducible Analysis of NGS data. Oficina (workshop). Automated and Reproducible Analysis of NGS data. Instituto Gulbenkian de Ciência.
2012/09/14 - 2012/09/16. Participação em evento. Course on Programming for Scientists. Oficina (workshop). Programming for Scientists. Instituto de Medicina Molecular João Lobo Antunes.
2012/05/28. Apresentação oral de trabalho. Gene expression and disease association analyses implicate EREG-AREG and NRG1 in susceptibility to Behçet’s Disease. XXXVII Jornadas Portuguesas de Genética.
2008/05/06. Apresentação oral de trabalho. Searching for a common genetic factor for Behçet’s disease and Ankylosing Spondylitis. . Marie Curie - Genome Architecture in Relation to Disease, Interplay among genetics, epigenetics and non-coding RNA's, .

Projetos

Projetos
2015/11/01 - 2019/05/31. Unveiling cis-regulatory variants role in breast cancer aetiology. Bolseiro de Pós-Doutoramento. Universidade do Algarve.
2018/06/01 - 2022/05/31. DEvoCancer: Decoding breast cancer evolution through mutant allele differential expression signatures, Concurso de Projetos de I&D em Todos os Domínios Científicos. Investigador. Universidade do Algarve.
2019/03/28 - 2023/03/27. Innovating breast cancer GWAS through inTEgRation of functional GENomics, 9471 - RIDTI. Investigador responsável. Universidade do Algarve.
2013/05 - 2015/10. Patients as Health Care Innovators: An Empirical Investigation of Treatment, Therapies and Medical Devices (TT&MD) developed by Patients of Chronic Diseases. Investigador. Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes.
2014/03/15 - 2015/10/31. Cis-regulation of somatic mutations in breast and ovarian cancers. Bolseiro de Pós-Doutoramento. Universidade do Algarve Centro de Investigação em Biomedicina.
2013/04/01 - 2013/06/30. Genetics of Nonsyndromic Cleft Lip and Palate NSCLP, 3599-PPCDT. Bolseiro de Técnico de Investigação. Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes; Fundação Calouste Gulbenkian; Hospital de São João.
2010/01/01 - 2013/04/30. BEDGET: decifrar a genética da doença de Behçet, 3599-PPCDT. Investigador. Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes; Fundação Calouste Gulbenkian.
2009/01/01 - 2012/12/31. IDENTIFICATION OF GENETIC RISK FACTORS FOR BEHÇETS DISEASE, PIDDAC. Universidade de Lisboa Faculdade de Medicina.
2008/04/01 - 2008/09/30. microRnómica e proteómica da doença de Parkinson, 3599-PPCDT. Bolseiro de Investigação. Fundação Calouste Gulbenkian; Instituto Gulbenkian de Ciência; Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes.

Produções

Esteves, Filipa; Xavier, Joana; Ford, AM; Rocha, Catia; Greaves, MF; Pharoah, P; Caldas, C; Chin, SF; Maia, Ana-Teresa. 2022. "Germline Allelic Expression of Genes at 17q22 Locus Associates with Risk of Breast Cancer". deposited at MedrXiv (2021), minor revisions at European Journal of Cancer. https://doi.org/10.1101/2021.12.10.21267625
Xavier, Joana M; Magno, Ramiro; Russel, Roslin; Almeida, Bernardo P; Jacinta-Fernandes, Ana; Duarte, André; Dunning, Mark; et al. 2022. "Mapping of cis-regulatory variants by differential allelic expression analysis identifies candidate risk variants and target genes of 27 breast cancer risk loci ". medrXiv. https://www.medrxiv.org/content/10.1101/2022.03.08.22271889v1
Correia L; Magno R; Xavier JM; de Almeida BP; Duarte I; Esteves F; Ghezzo M; et al. 2022. "Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant.". NPJ breast cancer. https://doi.org/10.1038/s41523-022-00435-9
2021. "Methods of analysis of polymorphisms associated with allelic expression of PIK3CA in cancer and uses thereof". Protegido.
Xavier, Joana; Magno, Ramiro; Russel, Roslin; de Almeida, Bernardo P.; Jacinta-Fernandes, Ana; Duarte, André; BARBOSA-MORAIS, NUNO; Maia, Ana-Teresa. 2021. Mapping of cis-regulatory variants by differential allelic expression analysis identifies regulatory variants and target genes of 31 breast cancer risk loci. Em EACR - Bioinformatics in Cancer. Virtual Event, Worldwide.
Jacinta-Fernandes, Ana; Xavier, Joana M.; Magno, Ramiro; Lage, Joel G.; Maia, Ana-Teresa. 2020. "Allele-specific miRNA-binding analysis identifies candidate target genes for breast cancer risk". npj Genomic Medicine, 5 (1). https://doi.org/10.1038/s41525-019-0112-9
Magno, Ramiro; Martel, Paulo; Ghezzo, Marinella; Xavier, Joana M; Maia, Ana-Teresa. 2020. Exploring the role of alternative splicing in breast cancer risk.. Em Cancer Biology: From Basic To Translational Research. .
Juliana Machado; Ramiro Magno; Joana M Xavier; Ana-Teresa Maia. 2019. Alternative splicing regulation by GWAS risk loci for breast cancer. https://doi.org/10.1101/766394
2019. "METHODS OF ANALYSIS OF POLYMORPHISMS ASSOCIATED WITH CANCER AND USES THEREOF". Protegido.
Xavier, Joana M; Magno, Ramiro; Rocha, Cátia L; Dunning, M; Russell, Roslin; Maia, Ana-Teresa. 2019. Mapping cis-regulatory variants pinpoints target genes of breast cancer risk loci. Em EMBO | EMBL Symposium: Systems Genetics: From Genomes to Complex Traits..
Esteves, Filipa; Xavier, Joana M; Maia, Ana-Teresa. 2019. DAE identifies COX11 and TOM1L1 as target genes in breast cancer risk locus 17q22. Em EMBL Conference: Cancer Genomics.
Matias, A.T.; Jacinta-Fernandes, A.; Magno, R.; Xavier, J.; Cabral, M.G.; Jacinto, A.; Maia, A.T.; Braga, S.. 2018. "Differential molecular signature in patients from African origin with triple-negative breast cancer". Em Annals of oncology : official journal of the European Society for Medical Oncology, viii95-viii95. https://doi.org/10.1093/annonc/mdy272.290
Xavier, Joana M; Magno, Ramiro; Almeida, Bernardo P.; Maia, Ana-Teresa. 2018. Integrative genomic approach elucidates the risk mechanism for breast cancer associated 5q14.1 locus. Em 3rd ASPIC International Congress.
Martins, Catarina; Xavier, Joana; Magno, Ramiro; Maia, Ana-Teresa. 2018. Identifying novel genes associated with Breast Cancer susceptibility using Allelic Expression Ratios. Em 3rd ASPIC International Congress.
Machado, J; Magno, R; Xavier, JM; Maia, AT. 2018. Uncovering the role of alternative splicing in Breast Cancer susceptibility. Em EMBL conference - Transcription and Chromatin.
Esteves, Filipa; Magno, Ramiro; Xavier, Joana M (EE13-176A-5613); Maia, Ana-Teresa. 2018. A comprehensive analysis of RNA-Seq data to identify risk variants for breast cancer using allelic expression. Em EMBL Conference: From Functional Genomics to Systems Biology.
Esteves, Filipa; Magno, Ramiro; Xavier, Joana M (EE13-176A-5613); Maia, Ana-Teresa. 2018. Identification of risk variants for breast cancer: a comprehensive analysis of RNA-Seq data. Em 3rd ASPIC International Congress.
Jacinta-Fernandes, A; Xavier, Joana M; Magno, Ramiro; Jerónimo, Carmen; Maia, Ana-Teresa. 2018. Revealing the role of allele- specific miRNA regulation in prostate cancer susceptibility. Em 3rd ASPIC International Congress..
Matias, A.T.; Jacinta-Fernandes, A.; Magno, R.; Xavier, J.; Cabral, M.G.; Jacinto, A.; Maia, A.T.; Braga, S.. 2018. "Differential molecular signature in patients from African origin with triple-negative breast cancer". Annals of Oncology, 29. https://doi.org/10.1093/annonc/mdy272.290
Abrantes, Patrícia; Rosa, Alexandra; Francisco, Vânia; Sousa, Inês; Xavier, Joana M.; Oliveira, Sofia A.. 2016. "Mitochondrial genome association study with peripheral arterial disease and venous thromboembolism". Atherosclerosis, 252: 97-105. https://doi.org/10.1016/j.atherosclerosis.2016.07.920
Xavier, J.; Almeida, B.; Sun, C.; Silva, J.; Marreiros, A.; Eldridge, M.; Bernards, R.; et al. 2016. "PIK3CA mutant allele differential expression (MADE) associates with breast cancer clinical features". Trabalho apresentado em EACR24: From basic research to precision medicine, Manchester, Reino Unido, 61. https://doi.org/10.1016/s0959-8049(16)61723-9
Rosa, A.; Abrantes, P.; Sousa, I.; Francisco, V.; Santos, P.; Francisco, D.; Xavier, J.M.; Oliveira, S.A.. 2016. "Ulcerative colitis is under dual (Mitochondrial and Nuclear) genetic control". Inflammatory Bowel Diseases, 22 (4): 774-781. https://doi.org/10.1097/MIB.0000000000000694
Abrantes, Patrícia; Santos, Maria M.; Sousa, Inês; Xavier, Joana M.; Francisco, Vânia; Krug, Tiago; Sobral, João; et al. 2015. "Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal". PLOS ONE, 10 (7). https://doi.org/10.1371/journal.pone.0133422
Xavier, Joana; Russell, Roslin; Almeida, Bernardo P.; Rosli, Nordiana; Rocha, Catia; Samarajiwa, Shamith; Chin, Suet-Feung; et al. 2015. "Integrative differential allelic expression analysis efficiently reveals the biology underlying risk to breast cancer". Em Mol Cancer Res, vol 61, Suppl 1 . https://doi.org/10.1158/1557-3125.advbc15-a31
Sousa, Inês; Shahram, Farhad; Francisco, David; Davatchi, Fereydoun; Abdollahi, Bahar Sadeghi; Ghaderibarmi, Fahmida; Nadji, Abdolhadi; et al. 2015. "Brief Report: Association ofCCR1,KLRC4,IL12A-AS1,STAT4, andERAP1With Behçet's Disease in Iranians". Arthritis & Rheumatology, 67 (10): 2742-2748. https://doi.org/10.1002/art.39240
Xavier, Joana M; Davatchi, Fereydoun; Abade, Olga; Shahram, Farhad; Francisco, Vânia; Abdollahi, Bahar Sadeghi; Trindade, Hélder; et al. 2015. "Characterization of the major histocompatibility complex locus association with Behçet’s disease in Iran". Arthritis Research & Therapy, 17 (1). https://doi.org/10.1186/s13075-015-0585-6
Xavier, J.M.; Shahram, F.; Sousa, I.; Davatchi, F.; Matos, M.; Abdollahi, B.S.; Sobral, J.; et al. 2015. "FUT2: Filling the gap between genes and environment in Behçet's disease?". Annals of the Rheumatic Diseases, 74 (3): 618-624. https://doi.org/10.1136/annrheumdis-2013-204475
Machado, Rui S. R.; Xavier, Joana M.; Futschik, Matthias E.. 2014. "Targeting molecular networks for drug research". Frontiers in Genetics, 5. https://doi.org/10.3389/fgene.2014.00160
Pinto, José P.; Reddy Kalathur, Ravi Kiran; Machado, Rui S. R.; Xavier, Joana M.; Bragança, José; Futschik, Matthias E.. 2014. "StemCellNet: an interactive platform for network-oriented investigations in stem cell biology". Nucleic Acids Research, 42 (W1): W154-W160. https://doi.org/10.1093/nar/gku455
Matos, Mafalda; Xavier, Joana M.; Abrantes, Patrícia; Sousa, Inês; Rei, Nádia; Davatchi, Fereydoun; Shahram, Farhad; et al. 2014. "IL10
low-frequency variants in Behçet's disease patients". International Journal of Rheumatic Diseases, 20 (5): 622-627. https://doi.org/10.1111/1756-185x.12369
Xavier, Joana Gonçalves de Gouveia Maia, 1984-. 2013. "Identification of genetic risk factors for Behçet’s disease". Doutoramento. http://hdl.handle.net/10451/10517
Xavier, J.M.; Krug, T.; Davatchi, F.; Shahram, F.; Fonseca, B.V.; Jesus, G.; Barcelos, F.; et al. 2013. "Gene expression profiling and association studies implicate the neuregulin signaling pathway in Behçet's disease susceptibility". Journal of Molecular Medicine, 91 (8): 1013-1023. https://doi.org/10.1007/s00109-013-1022-4
Xavier, Joana M.; Shahram, Farhad; Davatchi, Fereydoun; Rosa, Alexandra; Crespo, Jorge; Abdollahi, Bahar Sadeghi; Nadji, Abdolhadi; et al. 2012. "Association study of IL10 and IL23R-IL12RB2 in Iranian patients with Behçet's disease". Arthritis & Rheumatism, 64 (8): 2761-2772. https://doi.org/10.1002/art.34437
Xavier, J.M.; Shafiee, N.M.; Ghaderi, F.; Rosa, A.; Abdollahi, B.S.; Nadji, A.; Shahram, F.; Davatchi, F.; Oliveira, S.A.. 2011. "Association of mitochondrial polymorphism m.709GA with Behçet's disease". Annals of the Rheumatic Diseases, 70 (8): 1514-1516. https://doi.org/10.1136/ard.2010.143537
Krug, T.; Manso, H.; Gouveia, L.; Sobral, J.; Xavier, J.M.; Albergaria, I.; Gaspar, G.; et al. 2010. "Kalirin: A novel genetic risk factor for ischemic stroke". Human Genetics, 127 (5): 513-523. https://doi.org/10.1007/s00439-010-0790-y
Xavier, Joana Gonçalves de Gouveia Maia. 2008. "Estudo de linkage e pesquisa de mutações numa família portuguesa com doença de behçet e espondilite anquilosante". Mestrado. http://catalogo.ul.pt/F/?func=item-global&doc_library=ULB01&type=03&doc_number=000579887
 

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